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For more information, read this article which looks at the connection between thiamine deficiency and small intestinal bacterial overgrowth: When Sibo & Ibs-Constipation Are Just Unrecognized Thiamine Deficiency Thiamine also exerts direct effects on the intestinal barrier

Data confirmed the findings from the previous trial

CA, a diterpene compound, has been shown to exert strong antioxidant effects by reducing reactive oxygen species (ROS) and enhancing intracellular glutathione levels, which are essential for cellular redox balance and defense against oxidative damage

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When these pathways reactivate after deficiency, there may be increased demand for other nutrientsparticularly folate and iron

Funding This work was supported by the Minas Gerais State Agency for Research and Development FAPEMIG (BPD-0077722), the National Council for Scientific and Technological Development CNPq, and the Coordination of Superior Level Staff Improvement CAPES (Finance Code 001)