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Baicalein exerts therapeutic effects against endotoxin-induced depression-like behavior in mice by decreasing inflammatory cytokines and increasing brain-derived neurotrophic factor levels

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Since the AMPs are positively charged, attachment makes it displace cationic ions such as Ca 2+ and Mg 2+ , causing a disruption of the outer membrane, allowing the AMPs to reach the intracellular target (negatively charged phospholipids) [23,80]