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Ratios above were all according to volume

F.MaedaN.SmithiesO.et al

doi:10.1042/cs20180562 125

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An imbalance in the intestinal barrier structure can flare up into an uncontrollable immune reaction in the intestinal microenvironment or allow the unrestrained growth of microbiota, which leads to various diseases, including intestinal inflammatory disorders, extra-intestinal autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, and metabolic disorders such as diabetes and obesity 4,5,6

The researchers concluded that high blood glucose resulting from stress causes tissue-level insulin resistance, which leads to type 2 diabetes in patients with chronic stress states.20 Lifestyle Lifestyle factors can elevate cortisol because they're closely linked to stress