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Tumor growth is driven by intricate interactions between the tumor microenvironment (TME) and immune cells, inflammatory mediators, extracellular matrix remodeling, hypoxia, cancer stemness, cellular senescence, and metabolic dysregulation

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The binding energies between sulforaphane and the top 10 core targets are all -4.0 kcal/mol

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10.1016/j.bcp.2023.115664 183

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In its initial studies, Novo Nordisk found that cagrilintide led to more weight loss and better muscle preservation than semaglutide

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Expectation: Slow, modest improvements in endurance and substrate handling, when combined with regular training

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International Journal of Molecular Sciences, 17(12), 2141

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