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The molecular mechanisms of these chronic liver diseases are not clear, but the interaction of microbiota, gut-liver axis, and obesity is emerging as a mechanism of the development of obesity-related liver disease [41]

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A direct assessment of the blood pressure in the portal vein clearly showed that NaBPC157, as well as propranolol (given in all of the regimens), markedly prevented and/or decreased the otherwise increased portal blood pressure values in control rats

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