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Notably, Betulinic acid (BA), an autophagy modulator, has been shown to regulate autophagy and mitophagy through the AMPK-mTOR-TFEB signaling pathway, significantly inhibiting pyroptosis and facilitating functional recovery following SCI (100)

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doi: 10.3389/fonc.2022.950835

[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Kang M.A., So E.Y., Simons A.L., Spitz D.R., Ouchi T

[DOI] [PubMed] [Google Scholar] 198.Kumar M.R., Yeap S.K., Mohamad N.E., Abdullah J.O., Masarudin M.J., Khalid M., Leow A.T.C., Alitheen N.B

Recent studies have also focused on the role of various TCM herbs in modulating oxidative stress to slow aging