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The first works studying the molecular mechanisms underlying OR desensitization were reported more than 30 years ago (Gahwiler, 1981

In addition, the safety profile of antioxidant supplementation was favorable with minor side effects occurring in only 3.8% of patients, a rate comparable to placebo

Moderate heterogeneity was detected (I 2 = 52%, Q p = 0.048)

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These enzymes frequently require additional co-substrates or mediators that may limit their practical use for the decontamination of aflatoxins in food