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This approach can leave the patient vulnerable to severe infections and even certain types of cancer

Heyes et al
doi: 10.1007/s00134-015-3934-7

A., Mahadevan, S
A., & Stolzing, A
This limitation necessitates signal amplification strategies such as gold nanoparticles, conductive nanosheets, redox cycling, or heterostructure electrodes [155,156]