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Besides, the effect of gliadin on the enterocyte actin cytoskeleton was studied on rat intestinal epithelial (IEC-6) cell cultures, finding that it was able to reversible stimulate tyrosine phosphorylation of actin filaments resulting in filaments polymerization, cytoskeleton reorganization, and tight junction opening (254)
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Deckert J, Wetzel MC, Bartle LM, et al

HFpEF is a condition in which the hearts left pumping chamber becomes stiff and unable to fill properly
