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All these changes lead to cytokine storm characterized by increased expression and release of proinflammatory cytokines that participate in the pathogenesis of ARDS during virus respiratory infections like COVID-19

Pasternak et al

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Global, regional, and National burden of stroke and its risk factors, 19902019: a systematic analysis for the global burden of disease study 2019

The increased vascular permeability can be detected by measuring the extravasation of Evans blue dye

Buttar HS, Chow AY, Downie RH
