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Metallochaperones, an intracellular shuttle service for metal ions

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Introduction Diabetes mellitus (DM) is defined as a heterogeneous group of metabolic disorders characterized by an unusual hyperglycemia resulting from defects in insulin action and/or secretion

This also indicates a role of APLN/APLNR signaling in the regulation of immunological processes, which needs to be further investigated

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Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations