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The reason is that B12 in supplemental form can be absorbed without requiring stomach acid

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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Dignass AU, Sturm A

The last step in the production of adrenalin is the methylation of nor-adrenalin to produce methyl-nor-adrenalin or adrenalin by the enzyme Norepinephrine-N-methyl-transferase

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