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Zinc biochemistry: from a single zinc enzyme to a key element of life

Neuromuscular diseases Amyotrophic lateral sclerosis (ALS) ALS is a degenerative disease caused by gain of function mutations associated with a dominant SOD1 phenotype, a gene encoding the cytosolic antioxidant enzyme Cu, Zn-superoxide dismutase

L-carnitine protects neurons from 1-methyl-4-phenylpyridinium-induced neuronal apoptosis in rat forebrain culture

A more extensive, longer-term study found that patients with mild cognitive impairment scored better on the Mini-Mental Status Exam and the Sleep Disorders Index when taking melatonin [106]

Behavior experiments Animals were excluded from statistical analysis if data collection failed due to technical errors (e.g., equipment malfunction, improper sample handling, or missed experimental procedures)