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GSTs have emerged as a promising therapeutic target because specific isozymes are overexpressed in a wide variety of tumors and may play a role in the etiology of other diseases, including neurodegenerative diseases, multiple sclerosis, and asthma

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in addition, APAP overdoses in animals or in cell culture are used as popular models to

S-Acetyl-glutathione selectively induces apoptosis in human lymphoma cells through a GSH- independent mechanism

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