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The enzyme responsible for GSH recycling is glutathione reductase, which reduces glutathione disulfide (GSSG) back to the reduced GSH via consumption of NADPH (197)

Pan P-Y, Sheehan P, Wang Q, Zhu X, Zhang Y, Choi I, et al

SLC25A39 depletion inhibits subcutaneous xenograft growth in vivo To evaluate the effect of SLC25A39 on LUAD tumor growth in vivo, we established a xenograft model by subcutaneously injecting 2 10 6 A549 cellseither Cas9 control (Cas9C) or SLC25A39 knockout (koSLC25A39)into the left axilla of nude mice (n = 7 per group)

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Selective aging of the human cerebral cortex observed in vivo: differential vulnerability of the prefrontal gray matter