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As a follow-up to Lehninger's work several years later, Nishikimi and co-workers observed that the gene that codes for gulonolactone oxidase is actually present in humans, but is not active due to the accumulation of several mutations that turned it into a non-functional pseudogene (Nishikimi & Yagi 1991)

Effectiveness and tolerability of melatonin and zolpidem for the alleviation of jet lag

Geotimes 46(1):2427 Prospero JM, Bullard JE, Hodgkins R (2012) high-altitude dust over the north Atlantic: inputs from Icelandic proglacial dust storms

Acta Paediatrica

NSI-189 is an investigational benzylphenyl-aminopyridine derivative developed for its potential to stimulate neurogenesis in the hippocampus

Given that many PD-associated proteins regulate mitochondrial health, oxidative stress, and iron homeostasis, their dysregulation provides a direct mechanistic bridge to ferroptosis in PD progression ( Figure 3 )