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GLUT-4, glucose transporter 4

This mitochondrial dysfunction subsequently activates the c-Jun N-terminal Kinase (JNK)/p38 mitogen-activated protein kinase (p38) mitogen-activated protein kinase stress signaling pathway and triggers the release of cytochrome C, initiating the apoptotic cascade

The positive results observed in the studies could be due to both an increased mitochondrial fatty acid oxidation (which provides the sperm with more energy) and a reduced cell death in the testicles

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