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Specifically, recent research has suggested a bidirectional communication between metabolic dysfunction (loss of metabolic homeostasis) and cellular senescence ( In conclusion, the present results suggest new and unexpected links between fatigue, peripheral 5-HT, and L-carnitine in CFS and hypothyroidism, and offer testable hypotheses for future mechanistic and clinical studies

25 CaiJ.ShiG.ZhangY.ZhengY.YangJ.LiuQ.et al (2019)

Selenium speciation from food source to metabolites: A critical review

Mitochondria are both the major source of ROS production and a target for OS

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Although epilepsy was not assessed in the present study, these findings illustrate how metabolite-informed dietary strategies may support personalized nutritional approaches in ASD (Schoeler et al., 2021)
