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By subcutaneous (under the skin) injection to be given into the anterior half of the neck

Studies in humans and in animal models of MS suggest that male aged microglia do not have a higher propensity for inflammation, but may become more re-active at the rim of white matter lesions as a result of the presence of pro-inflammatory T cells, greater astrocyte activation or iron release from oligodendrocytes in the males

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The fragment does not bind the growth hormone receptor or activate the JAK2-STAT5 signaling pathway

doi: 10.1158/1535-7163.MCT-08-0013 137 StensonWFLobosE

Hurria, A., Fleming, M