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, Reference Flores2025)

In these lines, genetic modifications of astrocytes to foster their tissue-protective and anti-inflammatory functions have been proposed (70, 73, 84, 96, 148, 149, 288)

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This complex binds to E-box elements in target gene promoters to drive the rhythmic transcription of PER1, PER2, PER3, CRY1, and CRY2 (Shearman et al., 1997