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Identification in vitreous and molecular cloning of opticin, a novel member of the family of leucine-rich repeat proteins of the extracellular matrix

Although Compounds 1.62 and 1.63 lost the efficacy for a major detoxification process of GSH by being unable to interact with the GST enzyme, this does not indicate a loss for all the detoxification pathways

Therefore, hereditary risks should be evaluated by genetic analysis in these patients

10.1016/j.neuro.2016.09.010 [DOI] [PubMed] [Google Scholar] 27.Tsai CC, Wang MH, Chang KC, Soung HS, Yang CC, Tseng HC

As a result, altered intracellular glutathione homeostasis has been widely used as an indicator of oxidative stress