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The effects of vitamins, minerals, and physiological as well as plant secondary metabolites from nutrition or nutritional supplements on hair loss are still barely understood in detail and thus more scientific evidence is needed here [8] [11] [12]

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Sixty-four pathogenic variants described in the BLM gene include nucleotide insertions and deletions (41%), nonsense variants (30%), variants resulting in mis-splicing (14%), and missense variants (16%).[221,222] A specific pathogenic variant identified in the Ashkenazi Jewish population is a 6-bp deletion/7-bp insertion at nucleotide 2,281, designated as BLMASH .[223] Many of these variants result in truncation of the C-terminus, which prevents normal localization of this protein to the nucleus

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3 October 2018

*per meal amount based on 2 meals/day