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Description
Subsequent oxidation of TMA yields trimethylamine N-oxide (TMAO), a metabolite associated with increased vascular calcification risk
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AX may influence Polyunsaturated fatty acid (PUFA) metabolism through the modulation of fatty acid composition and the prevention of oxidative degradation rather than by directly stimulating PUFA biosynthesis [81]

Disruptions in any of these systems can lead to the accumulation of misfolded, damaged, or aggregated mitochondrial proteins, ultimately causing cellular dysfunction and contributing to diseases such as mitochondrial myopathies and cardiomyopathies 10,11,12

Statements Author contributions XF: Writing review & editing, Writing original draft, Conceptualization
