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Future studies are needed to reconcile the underlying differences between tumor tissue and basal PTC cell line GPX4 expression levels and in vitro responses to pharmacologic inhibition of GPX4 within an emulated 3D thyroid tumor microenvironment in vitro and in vivo

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A crucial piece of evidence comes from the study of the deprotonated molecules of heavy metal-biothiol conjugates ( i.e

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Packer (1982)