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It is also evident that many of the antioxidant enzymes are induced by GSH depletion at the transcriptional level which involves the binding of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) transcription factor to the antioxidant response element (ARE) in the promoter region of the genes encoding GCL and glutathione S -transferases [16]

Elesclomol-induced increase of mitochondrial reactive oxygen species impairs glioblastoma stem-like cell survival and tumor growth

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BP analysis was performed to functionally analyze the proteins differentially expressed in astrocytes between the OGD and OGD-allicin groups

[DOI] [PubMed] [Google Scholar] 100.Branzk N., Lubojemska A., Hardison S.E., Wang Q., Gutierrez M.G., Brown G.D., Papayannopoulos V

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