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Consistent with expectations, bona fide p53 targets including HDM2 and CDKN1A were among the most highly up-regulated genes in Control cells, whereas genes known to be negatively regulated by p53, such as E2F2 , were strongly down-regulated (el-Deiry et al, 1993

Introduction Neurodegenerative diseases (NDs) are the prominent source of disability and cause approximately 12% of all deaths at the global level

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Jul 1 1997 De Flora et al., European Respiratory Journal, doi:10.1183/09031936.97.10071535 Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment RCT 262 elderly and/or chronic disease patients in Italy showing significantly reduced frequency and severity of influenza-like episodes with 600mg N-acetylcysteine twice daily for 6 months