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An interspecies comparison

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. PLoS One 7(7):e42357

In contrast to free -Syn monomers, the presence of -Syn oligomers within exosomes facilitates enhanced cellular absorption and more efficient dissemination (Valencia et al., 2022)

The whole cell lysates were then immunoblotted with indicated antibodies

This fact is relevant as transgenic mice overexpressing IGFBP-2 were resistant to developing obesity when fed with high fat diet [174], suggesting that this molecule could have a direct effect on preadipocyte differentiation