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Description
The AT mechanism of all of the above-mentioned compounds usually involves conversion of manganese to an Mn IV -oxo form, which is then reducible by endogenous or exogenous AT (e.g., glutathione or vitamin C) activity (Halliwell and Gutteridge, 2015)
The reduction process is dependent on the composition of the platinum(IV) agents as well as the biological reducing agent involved
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Refinement of the coordinates against the diffraction data were done using phenix.refine in the PHENIX crystallographic software suite 64
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