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IP3Rs are known to contain the GSK3 consensus sequence for phosphorylation at Ser1756, which activates these channels and subsequently promotes Ca 2+ outflow from ER [26]

Parkinsons disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death

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Triptolide decreases rheumatoid arthritis fibroblast-like synoviocyte proliferation, invasion, inflammation and presents a therapeutic effect in collagen-induced arthritis rats via inactivating lncRNA RP11-83J16.1 mediated URI1 and -catenin signaling