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Fecal microbiota transplantation confirmed microbial causality but revealed donor-dependent effects, and engineered Lactobacillus expressing angiotensin-converting enzyme 2 (ACE2) or Ang-(17) preserved retinal integrity in diabetic models

Histological analyses revealed that a simultaneous ablation of these genes resulted in the presence of several hyperproliferative areas in the kidneys

Targeted delivery of the drugs used to treat these disorders could potentially offer a considerable redn

Non-canonical pyroptosis is initiated by the detection of intracellular lipopolysaccharide (LPS) from Gram-negative bacteria, leading to the activation of caspase 4 (CASP4) and caspase 5 (CASP5) in humans and caspase 11 (CASP11) in mice, which cleave GSDMD independently of inflammasome assembly

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[DOI] [PMC free article] [PubMed] [Google Scholar] 383.Pritchard J.B., Miller D.S