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Our result indicated that PREOG enhanced semen quality, GSI/EPI, SOD, GPx, and GST values at (PND90), also PREOG upregulates the expression of StAR, 3-HSD, 17-HSD genes, and testosterone value in (PND90), PREOG also upregulated the expression of PTMA, RSPH6A, DAAM1 genes, and the fertility outcome in (PND90) offspring

It is well recognized that the toxicity of arsenicals largely depends on the oxidoreduction states (trivalent or pentavalent) and methylation levels (monomethyl, dimethyl, and trimethyl) that are present during the process of metabolism in mammals

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