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Collectively, these findings position TB-500 as a relevant investigational model for examining microRNA-driven control of inflammation-associated intracellular signaling networks

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Procyanidin dimers are metabolized by human microbiota with 2-(3,4-dihydroxyphenyl)acetic acid and 5-(3,4-Dihydroxyphenyl)--valerolactone as the major metabolites

Such approaches hold translational potential for cancers harboring NMD-sensitive tumor suppressor mutations
