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Sphingosine may be phosphorylated to sphingosine-1-phosphate (S1P) by sphingosine kinase

10.1111/jnc.13643 73 Leyva-SotoA.Alejandra Chavez-SantoscoyR.PorrasO.Hidalgo-LedesmaM.Serrano-MedinaA.Alejandra Ramrez-RodrguezA.et al (2021)
(2025) Intellectual property rights in neuroprotective biomaterials

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OCT is also critical for monitoring treatment response, with changes in central subfield thickness serving as a key endpoint in clinical trials (115, 116)
