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Hur 2015), and a growing body of laboratory, animal, and human research indicates metformin may normalize the disturbed microbial balance associated with abnormal glucose metabolism (Pryor 2015
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doi: 10.1001/jamadermatol.2013.5588
In contrast, fixative staining methods provide reproducible data but are prone to errors due to the interference of autofluorescent species and the non-specific staining of cellular structures other than fat stores
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