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K11-Ub, placed on components of the TLR3- and STING-SCs enables OPTN recruitment, thereby promoting activation of TBK1, IRF3 and subsequent IFN induction

Conclusion The utilization of Arabidopsis thaliana as a conceptual framework has provided new perspectives for elucidating conserved signalling mechanisms associated with neurodegenerative processes

The buffer-exchanged PGRMC1 wild-type (apo and haem) and PGMRC1 C129S mutants were immediately analysed by nanoflow electrospray ionization MS using gold-coated glass capillaries made in house

Copper peptides are stable at neutral pH mixing these actives directly can reduce peptide effectiveness and increase irritation

Cancer Cell 37 , 767785 (2020)