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13 While reactive oxygen species are produced during normal daily metabolism, levels can also rise with prolonged exposure to ultraviolet and blue light-often associated with heavy use of screen-based devices such as computers and mobile phones
these populations include CMs, differentiated non-cardiac cell types, and undifferentiated hiPSCs [177]
[DOI] [PubMed] [Google Scholar] 11.Theparambil S.M., Weber T., Schmalzle J., Ruminot I., Deitmer J.W
The first step in the process involves the enzyme tyrosine hydroxylase which, like phenylalanine hydroxylase (of tyrosine synthesis), requires tetrahydrobiopterin (BH 4 , or also written H 4 B) as a cofactor
The appreciably high incidence of mitochondrial diseases highlights a growing need to devise effective therapeutic strategies
