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The human GSTP1 expressed in and purified from E

For passaging of organoids, the collagen domes were incubated with 1 mg ml 1 collagenase from Clostridium histolyticum (Sigma-Aldrich) for 30 min at 37 C, and digestion monitored using bright-field microscopy (small clumps of cells)

Neurosci Biobehav Rev 46 Pt 2: 202217, 2014

Rapamycin attenuates the progression of tau pathology in P301S Tau transgenic mice

However, results are not guaranteed, can take several months to become visible, and require consistent treatment to maintain

Emergency unblinding may only occur on an individual basis for safety reasons if the information can help the treatment of SAEs or SUSARs