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Description
AKT1 regulates UHRF1 protein stability and promotes the resistance to abiraterone in prostate cancer
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Of particular note is the presence of the protein HNRNPA1 (Heterogeneous nuclear ribonucleoprotein A1) in the network, a key RNA-binding protein that regulates the alternative splicing of PKM pre-mRNA, thereby favoring the formation of PKM2 mRNA over that of PKM1 41,42
[DOI] [PMC free article] [PubMed] [Google Scholar] Pani, P
Molecular Pharmacology
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