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HNE interacts directly with JNK isoforms in human hepatic stellate cells

Media and cultural conditions The bacterial strains were maintained as frozen glycerol stocks at 80 C

Pathways such as mTOR, AMPK, and the Beclin-1/PI3 K complex offer intriguing targets for the regulation of autophagy

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Brain research 1456 , 1421 (2012)

Cutting-edge directions and future prospects of neuronal metabolism research Looking ahead, integrating multi-omics approaches such as 4-dimensional fast data-independent acquisition (4D-FastDIA) quantitative proteomics and targeted metabolomics [e.g., dissecting how Danggui-Shaoyao-San regulates the glycogen synthase kinase 3 beta (GSK3)/PGC1 signaling pathway to improve brain glucose uptake and mitochondrial complex function in AD models (Wu et al., 2024)] with computational modeling is unraveling systematic regulatory networks in neuronal energy metabolism, pinpointing critical nodes like pyruvate dehydrogenase complex phosphorylation and dynamic MCT2 transporter expression (Brown and Ransom, 2007)