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Description
Activation of the oxidative stress pathway by HIV-1 Vpr leads to induction of hypoxia-inducible factor 1alpha expression

Cleare A, Pariante CM, Young AH, Anderson IM, Christmas D, Cowen PJ, Members of the Consensus Meeting, et al

The homogenate was filtered through a 100-M cell strainer and centrifuged at 1,000 g for 10 min at 4 C, then the nuclear pellet was washed once in nucleus preparation buffer followed by resuspension in PBS with 1% BSA and 0.2 U l Roche Protector RNase inhibitor

Potential Side Effects Epitalon is considered to have a high safety profile, with minimal side effects reported

Med Res Rev 40(1):158189

It is currently believed that inhibiting GPX4 by direct or indirect ways is the key to induce ferroptosis
