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Ultraviolet radiation increases generation of reactive oxygen and nitrogen species, which in turn enhance tyrosinase activity and thereby synthesis of melanin species within cells

Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine

Administering hepsin had a protective effect in both mouse models, reducing hepatotoxicity by modulating GJ abundance

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The link between GST overexpression, especially with respect to GSTP1, and anticancer drug resistance has been extensively studied

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