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Exploiting the excess ROS in epilepsy, tetrazine precursors formed hydrogelators that reacted with TCO-NB-GABA via bioorthogonal chemistry, releasing GABA at lesion sites [46]
Thus, in addition it would be helpful to measure free Cu in blood for monitoring therapeutic efficacy directly
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ClinicalTrialsRegister.eu [online], (2013)
J Neurosurg Sci 64(6):583585 Kesherwani V, Nelson KS, Agrawal SK (2013) Effect of sodium hydrosulphide after acute compression injury of spinal cord
Their dependency on the physiological state of the organism