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D-mannose, the monosaccharide naturally present in fruits such as cranberries, grapes and apples 22 , is generally regarded as safe and is commonly used as a dietary supplement, especially in urinary tract infections in women 127

If you're using other products, you should follow the directions if they have other active ingredients that may be too strong to use daily

"Hepatomegaly following short-term high-dose steroid therapy"

Roveri, A., Maiorino, M., Nisii, C

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Watch for Signs of Copper Toxicity While GHK-Cu is generally well tolerated, overexposure to copper (especially in individuals with impaired detox pathways) can cause symptoms such as: Nausea or gastrointestinal upset Headaches Mood swings or irritability Metallic taste in the mouth If any of these symptoms occur, discontinue use and contact your healthcare provider