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Drugs that exhibited statistically insignificant differences compared to the 0 Gy control (hits) with the glutathione assay were then tested with the senescence assay to discover library members that were efficacious in both assays (double hits)

Finally, the intensity ratio (r int ) is calculated as the quotient of signal intensity at the peak position (I peak ) divided by the mean signal intensity in the surrounding medium (I out )

doi: 10.1016/j.biopha.2022.114048 142 RenCTanPGaoLZengYHuSChenCet al

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[Google Scholar] Khan R.U., Shabana N., Dhama K

In light of this, the present review is intended to fully delineate the entire scope of cancer chemoprevention, and primarily focuses on various aspects of cancer chemoprevention based on natural compounds, specifically focusing on the mechanism of action of natural compounds in cancer prevention, and discussing in detail how they exert cancer prevention effects by affecting classical signaling pathways, immune checkpoints, and gut microbiome