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doi: 10.1093/jxb/erh202

Studies in inflammatory bowel disease models show KPV reducing intestinal inflammation markers without the systemic immunosuppressive effects associated with conventional treatments

In experimental DKD models, infliximab reduced albuminuria and attenuated glomerulosclerosis via suppression of ICAM-1-mediated leukocyte adhesion

Besides, BPC 157 therapy effects described in rats with bile duct cirrhosis and portal hypertension resulted in much less Ki-67- and alpha smooth muscle actin (-SMA) staining, counteracted disturbed cell proliferation and cytoskeletal structure in hepatic stellate cells, and showed a less disturbed collagen presentation, and thereby, less Mallory staining, and more hepatocytes where fewer had double nuclei[25]

R.RoesslerJ