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doi: 10.3389/fphar.2025.1693253 Received 26 August 2025 Revised 10 October 2025 Accepted 27 October 2025 Published 13 November 2025 Corrected 03 December 2025 Volume 16 - 2025 Edited by Lei Chen, Guangdong Ocean University, China Reviewed by Juexian Song, Capital Medical University, China Yingyi Zheng, Guangdong Provincial Hospital of Traditional Chinese Medicine, China Updates Copyright 2025 Wang, Gao, Zhang, Xiao, Chen, Shi, Yuan and Li

A novel brain-expressed protein related to carnitine palmitoyltransferase I

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(44) determined that the four kavalactones, kawain, methysticin, yangonin and desmethoxyyangonin, did not inhibit alcohol dehydrogenase in vitro , suggesting that interaction of kavalactones with alcohol does not involve alcohol dehydrogenase inhibition

Because glutathione can be broken down in the gut, liposomal delivery attempts to protect the compound and increase its availability inside the body

Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line