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5 and 6, all groups received 5 oral gavages with 50 mg grade III OVA (as above) in 0.2 ml PBS on days 14, 16, 18, 20 and 22

Activated microglia and astrocytes release proinflammatory cytokines including tumor necrosis factor-alpha (TNF- ), interleukin-6 (IL-6), and interleukin-1 (IL-1), creating a hostile neuroimmune milieu (Isik et al., 2023

Endothelial dysfunction is a significant characteristic of chronic illnesses including atherosclerosis and hypertension

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Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis