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It traditionally has been estimated using the Friedewald equation (LDL-C = total cholesterol minus HDL-C minus triglycerides/5), which becomes inaccurate at higher triglyceride levels and is invalid when triglycerides exceed 350400 mg/dL

Although it could be theoretically possible to enhance the reverse cholesterol effects of LXRs without targeting hepatic lipogenesis with the use of LXR-specific ligands since most of the hepatic responses are due to activation of LXR, this will be a difficult challenge as the ligand binding pocket in both isoforms has been shown to be nearly identical

Or perhaps you are the one who feels sleep-deprived in the morning, despite having spent seven or eight hours in bed

These negotiations with the enemy excited the suspicion of the Whigs and the fears of Congress