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S-acetyl glutathione is glutathione with an acetyl group attached to its sulfur atom

2008 doi: 10.1093/nar/gkm895

DNA damage builds up over time and increases PARP activity, which uses up NAD+ reserves

While safety monitoring was comprehensive, the trials were not specifically designed to detect rare adverse effects that might occur at rates lower than 1-2%, which would require much larger participant numbers

Glutathione and the intracellular labile heme pool
