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Following unilateral intrastriatal or medial forebrain bundle injection of 6-hydroxydopamine (6-OHDA)a classical neurotoxin used to mimic parkinsonian neurodegenerationthey observed pronounced leakage of FITC-labeled albumin and horseradish peroxidase into the ipsilateral striatum and substantia nigra at both 10 and 34 days post-lesion

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The broad pattern for acute injuries and post-surgical contexts in the data sits between four and eight weeks

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